NRP1 and neoplasm: A recent paper describing the effects of NRP1 antibodies that specifically block VEGF binding to the b1/b2 domain, concluded that the effects of NRP1 inhibition on endothelial cell function and angiogenesis appeared to be partly independent of VEGF, and also reported no effects of blocking NRP1 antibodies on tumour cell proliferation, but did not examine the effects on tumour cell migration and adhesion (Pan et al, 2007).