These included chemokine ligand IP-10 and genes controlled by pro-inflammatory cytokines TNF-α, IL-1β, IFN-γ; namely, interferon regulatory factor 1, Cd274 antigen, metallothionein 2, proteasome subunit (Psmb9), and tumor necrosis factor Tnfsf10 were progressively up-regulated after infection. The gene discussed is IRF1; the disease is infection.