POMC and infantile spasms: Agents that have been employed in the treatment of infantile spasms include benzodiazepams (especially nitrazepam), sodium valproate, vigabatrin (VGB), corticosteroids, ACTH, a ketogenic diet, vitamin B6, intravenous gammaglobulin, a benzodiazepam-carbamazepine cocktail, topiramate and zonisamide [2,5].