For example, two chromosomal translocations, t(2;13)(q35;q14) and t(1;13)(p36;q14), are associated with numerous alveolar rhabdomyosarcomas, the resulting fusion proteins (PAX3-FKHR and PAX7-FKHR) acquiring the capacity to inhibit MyoD and the subsequent differentiation of rhabdomyosarcoma cells [6], [7], [8]. The gene discussed is FOXO1; the disease is rhabdomyosarcoma.