Indeed Figure 2 shows that β43–63, but not the control peptide (scrambled β43–63), significantly (P<0.05) inhibited the length, number and area of tubules formed by EC activated by the five prominent angiogenic factors found in tumours (VEGF, PDGF-BB, EGF, FGF2 and HGF) on GF-reduced Matrigel, although β43–63 showed only minimal inhibition of EGF-induced tubule formation. The gene discussed is FGF2; the disease is neoplasm.