In an effort to better characterise the molecular implications of TMPRSS2–ERG fusions in prostate cancer and to identify other genetic prognostic markers, we have utilised RNA extracted from radical prostatectomy specimens in a prospective cohort previously characterised for TMPRSS2–ERG T1/E4 fusion transcript expression by qualitative PCR (Nam et al, 2007). This evidence concerns the gene ERG and prostate cancer.