This does not explain why silencing of PGRP-S1 and PGRP-S2/3 protects the mosquito from infection by Staphylococcus aureus, that displays Lys-type peptidoglycan, but not from infection by Escherichia coli (Dap-type peptidoglycan) [32]. The gene discussed is PGLYRP1; the disease is infection.