Because it seemed possible that dysregulation of any one of these proteins might result in increased ROS accumulation and/or unrepaired DNA damage and could feasibly promote oncogenesis, we examined their expression as well as the damage markers 8-OxoG, γ-H2AX and nitrotyrosine, in normal mammary tissue, BH, DCIS and IBC. Here, H2AX is linked to inflammatory breast carcinoma.