FOXP3 and nasopharyngeal carcinoma: We have demonstrated that the number of Foxp3+TIL (Treg) was significantly associated with a favorable outcome (OS and PFS) in Chinese NPC patients (Fig 2); this association was correlated with the disease stage since Foxp3 was a favorable factor for survival in late stage patients but no significant influence on the early stage patients (Fig 3B, P < 0.01).