NR3C2 and fungal infectious disease: To explore the role of Dectin-1 and the MR in the control of fungal infection by alternatively activated macrophages (M2), we studied the phagocytosis of non-opsonized C.albicans and the production of yeast-induced reactive oxygen species (ROS) by macrophages, in the presence or absence of soluble receptor blocking agents (laminarin and mannan).