Terabe and Berzofsky single out IL-13, produced by type II NKT cell in several mouse tumor models, as an important immunosuppressive cytokine, inducing CD11b+Gr-1+ myeloid lineage to secrete TGF-β that finally inhibits CTL induction against the tumor [8], [24], [25]. The gene discussed is ITGAM; the disease is neoplasm.