In addition, the erythrocyte count, hemoglobin and hematocrit levels went down to 2 to 4 × 106/mm3 (P = 0.01), 3-7 g/dl (P = 0.01), 13% (P = 0.01), respectively, suggesting that THOC5/FMIP depleted mice died from hematological disorders such as anemia, and internal bleeding. The gene discussed is THOC5; the disease is anemia (phenotype).