This anti-insulin-like growth factor I receptor antibody, together with paclitaxel and carboplatin, was suggested to be safe and showed promising effectiveness in patients with non-small-cell lung cancer (NSCLC) showing the highest overall response rate of 78% in squamous cell carcinoma and 58% in adenocarcinomas [71]. The gene discussed is IGF1R; the disease is non-small cell lung carcinoma.