ACHE and Parkinson disease: Besides inhibiting acetylcholinesterase (Milatovic et al. 2006; Singh and Agarwal 1983), carbamate (Zhou et al. 2004) and OP (Sharma et al. 2005) pesticides are suspected to be involved in the etiologic pathway leading to PD, for example, by disturbing redox processes that inhibit antioxidant enzymes, thus enhancing lipid peroxidation and oxidative stress (Lukaszewicz-Hussain 2008) or inhibiting the proteasome or mitochondrial function in neurons.