Thus, the presence of high level of CXCL12 in the ascitic fluids as well as the inhibition of intraperitoneal dissemination of ovarian cancer xenografts by CXCR4 antagonist suggests that CXCR4/CXCL12 axis may be important in the invasion of ovarian cancer cells and further studies will be necessary to better deepen this important question. The gene discussed is CXCR4; the disease is ovarian carcinoma.