In ovarian cancer, the existence of a direct relationship between the expression of angiogenic molecules and the pathological behavior of five different human ovarian cancers, xenografted in the peritoneal cavity of nude mice, was reported, demonstrating that the expression of CXCL8/IL-8 was associated with neovascularization and inversely correlated to survival [75]. The gene discussed is CXCL8; the disease is ovarian carcinoma.