However, after stratification by egg intake, reduced RCC risk was observed with increasing consumption frequency of eggs among subjects with ≥1 variant rs1007971 (P-trend <.001), rs3118523 (P-trend <.001), rs748964 (P-trend <.001), rs3118536 (P-trend <.001), and rs10776909 (P-trend = .004) allele across the RXRA gene. Here, RXRA is linked to renal cell carcinoma.