Besides confirming the previously known T2D loci PPARG[4], TCF7L2[7] and KCNJ11[8], the GWA studies have identified new loci CDKAL1, CDKN2A/CDKN2B, IGF2BP2, FTO, SLC30A8 and HHEX[9]–[12] that influence the risk of T2D. This evidence concerns the gene HHEX and type 2 diabetes mellitus.