We have selected polymorphisms in nine T2D genes, CDKAL1, CDKN2A/CDKN2B, FTO, HHEX, IGF2BP2, KCNJ11, PPARG, SLC30A8 and TCF7L2. Two of these genes, PPARG and KCNJ11, are well-established candidate genes involved in T2D pathways, while the other seven were discovered in initial GWAS and therefore should explain a large fraction of T2D cases. This evidence concerns the gene HHEX and type 2 diabetes mellitus.