1), chemically, (3S)-2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride1, is an angiotensin converting enzyme (ACE) inhibitor, used to treat hypertension and cardiac failure2, 3. This evidence concerns the gene ACE and hypertensive disorder.