A portion of the coding sequence for dysbindin gene (rs3213207; rs1011313; rs760761; rs16876759; rs2619522) was chosen on the basis of evidence of an association between dysbindin and depressive spectrum disorders, bipolar disorder and schizophrenia.16-19 Genetic investigations were performed on Korean patients with bipolar disorder. The gene discussed is DTNBP1; the disease is bipolar disorder.