TP53 and osteosarcoma: To assess the functional significance of miR-24, we evaluated its effect on cellular proliferation using six different cancer cell lines; four human colon cancer cell lines [HCT-116 (wt-p53), HCT-116 (null-p53), RKO (wt-p53) and HT-29 (mut-p53)] and two human osteosarcoma cell lines [U2OS (wt-p53) and MG63 (null-p53)].