Amongst the other signals of association with T2D identified through application of the multinomial regression model (Table II), two regions demonstrate clear evidence of heterogeneity in allelic odds ratios between obese and non-obese cases: variants close to CAND1 (lead SNP rs11176733, with multinomial P = 2.2 × 10−6) and variants in CCDC33 (lead SNP rs901130, with multinomial P = 5.5 × 10−6). Here, CCDC33 is linked to type 2 diabetes mellitus.