Patients with JE are typically admitted to hospital 3 to 4 days after illness onset so the 10th day of illness corresponds to day 7 after hospital admission [24,43], and another study, measuring from day of admission, found 100% (19/19) of JE patients had IgM in serum on day 7 after admission compared with 53% on day 1 [39]. Here, CD40LG is linked to Japanese encephalitis.