Among our examined patients IgE-mediated allergy specific to particular food was diagnosed in 21% of patients with Crohn's disease and in over 32% of patients with ulcerative colitis; the features of atopy in the form of sole high IgE was found twice more often in patients with Crohn's disease, they are probably connected with immunologic disorders occurring in the course of disease; we obtained similar results in the previously published studies [22]. The gene discussed is IGHE; the disease is ulcerative colitis.