RNASE3 and inflammatory bowel disease: In IBD eosinophils usually comprise a small percentage of predominant lymphocytic infiltration, but their high level is a predictor of unfavourable prognosis, since the products of their degranulation, such as eosinophil cationic protein, have a proinflammatory effect and damage tissues; degranulation of eosinophils was also observed in the course of IBD [17, 18].