Gene expressions were markedly increased in pancreatic cancer tissues compared to normal pancreatic tissues (CD4: 150 transcripts ± 28.1 in pancreatic cancer vs. 52 transcripts ± 12.4 in normal pancreas; CD8: 171 transcripts ± 30.2 in pancreatic cancer vs. 39 transcripts ± 6.4 in normal pancreas). Here, CD8A is linked to familial pancreatic carcinoma.