CDH1 and metastatic malignant neoplasm in the lymph nodes: Tumors with reduced E-cadherin expression invaded deeper (P < 0.0001), had more lymph node metastasis (P < 0.0001), had more distant nodal metastasis (P = 0.002), had a more advanced stage (P < 0.0001) and had more lymphatic invasion (P = 0.0008) than those that were preserved E-cadherin expression.