CENP-H expression was higher in tongue cancer cell lines and nasopharyngeal carcinoma cell lines [20,21]Therefore, to study centromere proteins may contributes to exploring the mechanism of chromosome segregation, revealing the mechanism of malignant cellular proliferation and finding cancer marker proteins, and also may provide new targets for carcinoma therapy and prognosis estimation of cancer patients. This evidence concerns the gene CENPH and nasopharyngeal carcinoma.