TP53 and breast cancer: Within the patient group with p53-positive tumors, breast cancer-specific survival stratified by TP53 R72P seemed to show inconsistent results between studies though none were significant, that is, per allele HR (adjusted for age, stage, grade and ER) in the ABCS study was 0.74 (0.45 to 1.22) and in the HEBCS study 1.46 (0.79 to 2.69).