Thus, Baudouin et al. [25], by analysing 150 individuals who were sequentially admitted to an intensive care unit in the UK and 542 age-matched controls, determined that mtDNA hg H was a strong independent predictor of outcome during severe sepsis, conferring a 2.12-fold (95% CI 1.02–4.43) increased chance of survival at 180 days compared with individuals without hg H. More recently, Yang et al. [26] claimed that hg R can predict survival advantage in severe sepsis, a conclusion derived from the prospective analysis of 181 Han patients recruited in an intensive care unit. Here, GDF15 is linked to Sepsis.