The NFKBIL1, a divergent member of I-κ-B proteins that is an inhibitor for NFKB complex, may have potential interaction between MIF and NFKBIL1. In Figure 1, we showed that the indirect connection between MIF and NFKBIL1 via VEGF. Furthermore, the relation between TNF and NFKB-dependent signaling pathway of RA patients was discussed by Youn et al. [20]. This evidence concerns the gene NFKB1 and rheumatoid arthritis.