CSMD1 and Insulin resistance: As shown in Figure 1, the strongest associations in terms of effect size and statistical significance were found between CETP and Lipids (βstd = 0.15 ± 0.02; p = 1.04 × 10-8), STARD13 and Insulin Resistance (βstd = 0.14 ± 0.08; p = 0.05), and STARD13 and MetSyn (βstd = 0.08 ± 0.03; p = 0.007); however, the CSMD1 latent construct was not associated with MetSyn even when using different combinations of SNPs to devise the construct (data not shown).