Using unrelated cases and controls from the North American Rheumatoid Arthritis Consortium (NARAC) [12] provided by the Genetic Analysis Workshops 16 and previously analyzed by Plenge et al. [4], we sought to find non-HLA-DRβ1 genetic associations separately in SE positive and SE negative individuals. This evidence concerns the gene HLA-DRB1 and rheumatoid arthritis.