Examples include: imidazoquinolines (Imiquimod and Resiquimod), which target Toll-like receptors (TLRs), specifically TLR-7 and-8, and were developed as nucleoside analogues for anti-viral or anti-tumour therapy; Bestatin (a tumour adjuvant acting as an inhibitor of aminopeptidase N [CD13]); Levamisole and Bupivacaine (both DNA vaccine adjuvants). This evidence concerns the gene TLR7 and neoplasm.