In addition to a faster MSP119-specific IgG ASC response, the secondary response was composed predominantly of IgG ASC, (97%, 93% and 83% of all anti-MSP119 ASC at days 10, 20 and 30 of secondary infection respectively), in contrast to the primary response which contained a large IgM component (Figure 6B, i–iv). The gene discussed is CD40LG; the disease is infection.