PSMB6 and cancer: Looking for tissue-specific alteration in proteasome units, researchers treated mice with 3H-1,2-dithiole-3-thione (D3T), which functions as a cancer preventive agent proved both in animal and human studies; 24 h later, expression of the 20S catalytic core subunits PSMB5, PSMB6 and PSMB7 were increased in liver, lung, small intestine and colon of mice (Kwak et al, 2007a).