It was reported that basal-like and BRCA1-associated breast carcinomas, which are also related (Foulkes et al, 2003) were both enriched with CD44+/CD24− candidate stem cells (Honeth et al, 2008), and BRCA1 has been suggested to represent a stem cell regulator (Foulkes, 2004). The gene discussed is BRCA1; the disease is breast carcinoma.