We found that although Id-1 was again significantly correlated with Gleason grade of individual cores in our cohort (Table 2a, r=0.356, P<0.001), TNF-β did not correlated with either Gleason score of the tumours (r=−0.028, P=0.709) or Gleason grade of the individual cores (Table 2b, r=−0.04, P=0.532). This evidence concerns the gene LTA and neoplasm.