When a submucosal tumor is found incidentally during upper endoscopy or colonoscopy, the extraluminal extent of disease should be evaluated using CT.[6] The diagnosis of GIST is secured by immunohistochemical staining for the tyrosine kinase receptor KIT (CD 117), which highlights the presence of interstitial cells of Cajal (ICC). This evidence concerns the gene NTRK1 and gastrointestinal stromal tumor.