We evaluated HPV detection in DNA from three common types of genital clinical samples; directly comparing genital warts, CIN (cervical intra-epithelial neoplasia) brushings and VIN (vulval intra-epithelial neoplasia) lesions using the MY09/11, GP5+/6+ and PGMY09/11 primer sets in primary PCR and with subsequent comparison with a nested PCR approach (PGMY-GP) [25]. Here, GP5 is linked to anogenital human papillomavirus infection.