XRCC1 and lung adenocarcinoma: In the present study, we found that non-smoking female lung adenocarcinoma patients with AA genotype at XRCC1 Arg399Gln had a shorter survival time (9.23 months vs. 19.10 months) and higher risk of death (adjusted HR = 2.68, 95%CI = 1.79-4.02) than those with GG genotype.