TNFSF13 and neoplasm: In contrast, expression of APRIL protein in the tumour stroma was associated with poor survival (n = 234, p = 0.019, figure 3a), including in stage III patients (n = 102, p = 0.016, figure 3b), but was not associated with survival in Stage I or II (n = 46 p = 0.601 and n = 86 p = 0.440, respectively, Additional File 7).