Although rhizomelia has been described in some types of osteogenesis imperfecta [4],[5], we did not observe differences in the ratio of femur to tibia lengths in CypB-deficient mice compared to littermate controls (0.819±0.027 vs. 0.826±0.013) (Figure S2B). The gene discussed is PPIB; the disease is osteogenesis imperfecta.