MMP-2 expression was significantly higher in ameloblastic carcinoma (100%) and ameloblastoma (84.06%) than in KCOT (18.75%, P < 0.01), but was not significantly different in primary ameloblastoma (82.22%) versus recurrent ameloblastoma (87.5%) or between histological types (Table 1). This evidence concerns the gene MMP2 and ameloblastoma.