IFIH1 and Alzheimer disease: Therefore and in order to determine whether IFIH1 rs1990760 polymorphism is involved in the genetic background of other endocrine autoimmune disease we compared genotype and allele frequencies in German patients with Graves' disease (GD), Hashimoto's thyroiditis (HT), Addison's disease (AD) and healthy controls (HC) and performed transmission disequilibrium tests (TDT) for that polymorphism in families with GD (German) and families with HT (Italian).