We identified three different NKD1 exon 10 coding region mutations in 5/11 CRC cell lines and 2/40 sporadic CRC tumors with MSI (Table 1), but no NKD1 coding region or splice junction mutations in 5/5 CRC cell lines and 50/50 tumors without MSI. This evidence concerns the gene NKD1 and colorectal carcinoma.