Figure 2a shows the mean VEGF concentration was lower in children with tricuspid regurgitation velocity ≥2.60 m/sec than those with velocity <2.60 m/sec after adjustment for PDGF-BB, hemolytic index and interleukin-6. In contrast, Figure 2b–d shows that the adjusted mean values for PDGF, interleukin-6 and hemolytic index were higher with tricuspid regurgitation velocity ≥2.60 m/sec. The gene discussed is VEGFA; the disease is Tricuspid regurgitation.