IRF5 and rheumatoid arthritis: For RA; PRKCQ and GZMB (these showed nominal significance P<10−4 to 10−5 in the WTCCC study), IL2RA, IL2RB and TNFAIP3 (these showed a modest evidence of association P<10−5 to 5×10−7 in WTCCC study), and MICA [29]–[31] as well as IRF5 [32], [33] that was confirmed by meta-analysis [34].