PDZK1 and myocardial infarction: To determine if the relatively high abundance of severely occluded arteries in PDZK1/apoE dKO mice were associated with higher incidence of myocardial infarction, we stained cardiac sections of both PDZK1/apoE dKO and apoE single KO mice with Masson trichrome to identify areas of myocardial infarction and fibrosis (blue stain, Fig. 4, D–E).