In HeLa cervical cancer cells an LD50VM26 of 0.3 μM was measured with Bmi1 siRNA compared to 3.5 μM with a control siRNA, and in A549 lung cancer cells an LD50VM26 of 1.1 μM was measured with Bmi1 siRNA compared to 7.4 μM with the control siRNA. The gene discussed is BMI1; the disease is lung carcinoma.