BMI1 and lung cancer: In HeLa cervical cancer cells an LD50VM26 of 0.3 μM was measured with Bmi1 siRNA compared to 3.5 μM with a control siRNA, and in A549 lung cancer cells an LD50VM26 of 1.1 μM was measured with Bmi1 siRNA compared to 7.4 μM with the control siRNA.