To examine the cytolytic effects of MEDI-565, the CEA+ human pancreatic cancer cell line AsPC-1 was incubated with purified, human T cells and MEDI-565 or a control BiTE (which binds the herbicide mecoprop and human CD3; Cont BiTE) for 5 days. Here, CEACAM5 is linked to familial pancreatic carcinoma.