However, the replication with asthma was only found in NPSR1 and PHF11 in both cohorts, yet for NPSR1, the opposite alleles of SNPs were associated in either cohort, and for PHF11, there was no overlap in the associated SNPs across the two cohorts; no association was found in ADAM33, DPP10 or HLA-G in either cohort. This evidence concerns the gene HLA-G and asthma.